Oxidative Stress & Male Reproductive Health
Irrefutable evidence suggests that human semen quality is declining and thereby raising
the possibility that, in a few decades, men will have to freeze their sperm at a young age to
ensure adequate semen quality. In a recent study, oxidative stress was implicated in some 60% of men seeking assistance with their fertility.
Collective scientific evidence overwhelmingly implicates oxidative stress in the etiology of poor reproductive health and consequently the diminished quality of sperm and egg. The optimum resolution of oxidative stress may only be possible with a specific synergistic combination of antioxidants normally present in healthy cells or tissues.
The causes of sperm oxidative DNA damage are both environmental and pathophysiological. Modern synthetic lifestyle, poor nutrition and smoking are examples of environmental factors whereas age, obesity, infection, fever, cancer, varicocele are known pathophyiological factors.
Over the last decade, CellOxess and its academic collaborators have engaged in scientific and clinical evaluation of the assays measuring sperm DNA integrity in male volunteers and patients in centers in Australia, the UK and the US. Simultaneously, our academic collaborators in France and Spain are studying sperm oxidative stress in rodents to help us further understand the role it plays in male reproductive health. CellOxess is currently developing new assay technologies to assess sperm oxidative stress. Likewise, the DNA damage inducing factors are numerous and highly varied in nature. CellOxess scientists believe the most effective approach is to restore the natural antioxidant defense mechanism throughout the duration of spermatogenesis. Based on extensive research, CellOxess now offers a unique natural polyantioxidant supplement to combat sperm oxidative stress and promote the development of healthy sperm cells in the male reproductive tract.
Oxidative Stress & Female Reproductive Health
Oxidative Stress & Equine Reproductive Health